Early Cytokine Induction Upon Pseudomonas aeruginosa Infection in Murine Precision Cut Lung Slices Depends on Sensing of Bacterial Viability

Early Cytokine Induction Upon Pseudomonas aeruginosa Infection in Murine Precision Cut Lung Slices Depends on Sensing of Bacterial Viability

Breathing allows a multitude of airborne microbes and microbial compounds to access the lung. Constant exposure of the pulmonary microenvironment to immunogenic particles illustrates the need for proper control mechanisms ensuring the differentiation between threatening and harmless encounters. Disc...

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Bibliographic Details
Main Authors: Ulrike Kolbe, Buqing Yi, Tanja Poth, Amy Saunders, Sébastien Boutin, Alexander H. Dalpke
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
precision cut lung slice
Pseudomonas aeruginosa
live/dead discrimination
innate immunity
infection and immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.598636/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.598636/full

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