Prediction of antibacterial activity from physicochemical properties of antimicrobial peptides.

Consensus is gathering that antimicrobial peptides that exert their antibacterial action at the membrane level must reach a local concentration threshold to become active. Studies of peptide interaction with model membranes do identify such disruptive thresholds but demonstrations of the possible co...

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Bibliographic Details
Main Authors: Manuel N Melo, Rafael Ferre, Lídia Feliu, Eduard Bardají, Marta Planas, Miguel A R B Castanho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22194847/?tool=EBI