Identification of <it>Pou5f1</it>, <it>Sox2</it>, and <it>Nanog </it>downstream target genes with statistical confidence by applying a novel algorithm to time course microarray and genome-wide chromatin immunoprecipitation data

<p>Abstract</p> <p>Background</p> <p>Target genes of a transcription factor (TF) <it>Pou5f1 </it>(<it>Oct3/4 </it>or <it>Oct4</it>), which is essential for pluripotency maintenance and self-renewal of embryonic stem (ES) cells, have p...

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Bibliographic Details
Main Authors: Xin Li, Matoba Ryo, Aiba Kazuhiro, Piao Yulan, Sharova Lioudmila V, Masui Shinji, Sharov Alexei A, Niwa Hitoshi, Ko Minoru SH
Format: Article
Language:English
Published: BMC 2008-06-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/9/269