Identification of <it>Pou5f1</it>, <it>Sox2</it>, and <it>Nanog </it>downstream target genes with statistical confidence by applying a novel algorithm to time course microarray and genome-wide chromatin immunoprecipitation data
<p>Abstract</p> <p>Background</p> <p>Target genes of a transcription factor (TF) <it>Pou5f1 </it>(<it>Oct3/4 </it>or <it>Oct4</it>), which is essential for pluripotency maintenance and self-renewal of embryonic stem (ES) cells, have p...
Main Authors: | , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2008-06-01
|
Series: | BMC Genomics |
Online Access: | http://www.biomedcentral.com/1471-2164/9/269 |