Enhanced human tissue microdialysis using hydroxypropyl-ß-cyclodextrin as molecular carrier.

Enhanced human tissue microdialysis using hydroxypropyl-ß-cyclodextrin as molecular carrier.

Microdialysis sampling of lipophilic molecules in human tissues is challenging because protein binding and adhesion to the membrane limit recovery. Hydroxypropyl-ß-cyclodextrin (HP-ß-CD) forms complexes with hydrophobic molecules thereby improving microdialysis recovery of lipophilic molecules in vi...

Full description

Bibliographic Details
Main Authors: Marcus May, Sandor Batkai, Alexander A Zoerner, Dimitrios Tsikas, Jens Jordan, Stefan Engeli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3618094?pdf=render

Internet

http://europepmc.org/articles/PMC3618094?pdf=render

Similar Items