Identification of a receptor for extracellular renalase.

BACKGROUND:An increased risk for developing essential hypertension, stroke and diabetes is associated with single nucleotide gene polymorphisms in renalase, a newly described secreted flavoprotein with oxidoreductase activity. Gene deletion causes hypertension, and aggravates acute ischemic kidney (...

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Bibliographic Details
Main Authors: Ling Wang, Heino Velazquez, John Chang, Robert Safirstein, Gary V Desir
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4407985?pdf=render