Variability in the precore and core promoter regions of HBV strains in Morocco: characterization and impact on liver disease progression.

BACKGROUND: Hepatitis B virus (HBV) is one of the most common human pathogens that cause aggressive hepatitis and advanced liver disease (AdLD), including liver cirrhosis and Hepatocellular Carcinoma. The persistence of active HBV replication and liver damage after the loss of hepatitis B e antigen...

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Main Authors: Bouchra Kitab, Abdellah Essaid El Feydi, Rajaa Afifi, Christian Trepo, Mustapha Benazzouz, Wafaa Essamri, Fabien Zoulim, Isabelle Chemin, Hanane Salih Alj, Sayeh Ezzikouri, Soumaya Benjelloun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3419231?pdf=render