Prolactin induces apoptosis of lactotropes in female rodents.

Anterior pituitary cell turnover occurring during female sexual cycle is a poorly understood process that involves complex regulation of cell proliferation and apoptosis by multiple hormones. In rats, the prolactin (PRL) surge that occurs at proestrus coincides with the highest apoptotic rate. Since...

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Bibliographic Details
Main Authors: Jimena Ferraris, Sandra Zárate, Gabriela Jaita, Florence Boutillon, Marie Bernadet, Julien Auffret, Adriana Seilicovich, Nadine Binart, Vincent Goffin, Daniel Pisera
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4032245?pdf=render