Opa1 relies on cristae preservation and ATP synthase to curtail reactive oxygen species accumulation in mitochondria

Opa1 relies on cristae preservation and ATP synthase to curtail reactive oxygen species accumulation in mitochondria

Reactive oxygen species (ROS) are a common product of active mitochondrial respiration carried in mitochondrial cristae, but whether cristae shape influences ROS levels is unclear. Here we report that the mitochondrial fusion and cristae shape protein Opa1 requires mitochondrial ATP synthase oligome...

Full description

Bibliographic Details
Main Authors: Rubén Quintana-Cabrera, Israel Manjarrés-Raza, Carlos Vicente-Gutiérrez, Mauro Corrado, Juan P. Bolaños, Luca Scorrano
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Redox Biology
Subjects:
Mitochondrial cristae
Ultrastructure
ROS
Opa1
F1FO-ATP synthase
Bioenergetics
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231721000926

Internet

http://www.sciencedirect.com/science/article/pii/S2213231721000926

Similar Items