Microevolution of Candida albicans in macrophages restores filamentation in a nonfilamentous mutant.

Microevolution of Candida albicans in macrophages restores filamentation in a nonfilamentous mutant.

Following antifungal treatment, Candida albicans, and other human pathogenic fungi can undergo microevolution, which leads to the emergence of drug resistance. However, the capacity for microevolutionary adaptation of fungi goes beyond the development of resistance against antifungals. Here we used...

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Bibliographic Details
Main Authors: Anja Wartenberg, Jörg Linde, Ronny Martin, Maria Schreiner, Fabian Horn, Ilse D Jacobsen, Sabrina Jenull, Thomas Wolf, Karl Kuchler, Reinhard Guthke, Oliver Kurzai, Anja Forche, Christophe d'Enfert, Sascha Brunke, Bernhard Hube
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-12-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1004824

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https://doi.org/10.1371/journal.pgen.1004824

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