The Free Hormone Hypothesis: When, Why, and How to Measure the Free Hormone Levels to Assess Vitamin D, Thyroid, Sex Hormone, and Cortisol Status
ABSTRACT The free hormone hypothesis postulates that only the nonbound fraction (the free fraction) of hormones that otherwise circulate in blood bound to their carrier proteins is able to enter cells and exert biologic effects. In this review, I will examine four hormone groups—vitamin D metabolite...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | JBMR Plus |
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| Online Access: | https://doi.org/10.1002/jbm4.10418 |