Role of aberrant metalloproteinase activity in the pro-inflammatory phenotype of bronchial epithelium in COPD
<p>Abstract</p> <p>Background</p> <p>Cigarette smoke, the major risk factor for COPD, is known to activate matrix metalloproteinases in airway epithelium. We investigated whether metalloproteinases, particularly A Disintegrin and Metalloproteinase (ADAM)17, contribute t...
Main Authors: | Postma Dirkje S, Slebos Dirk-Jan, Noordhoek Jacobien A, Brandenburg Simone M, Heijink Irene H, van Oosterhout Antoon J |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-08-01
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Series: | Respiratory Research |
Subjects: | |
Online Access: | http://respiratory-research.com/content/12/1/110 |
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