Efficacy of Prednisolone in Generated Myotubes Derived From Fibroblasts of Duchenne Muscular Dystrophy Patients

Efficacy of Prednisolone in Generated Myotubes Derived From Fibroblasts of Duchenne Muscular Dystrophy Patients

Duchenne muscular dystrophy (DMD) is a recessive X-linked form of muscular dystrophy characterized by progressive muscle degeneration. This disease is caused by the mutation or deletion of the dystrophin gene. Currently, there are no effective treatments and glucocorticoid administration is a standa...

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Bibliographic Details
Main Authors: Tsubasa Kameyama, Kazuki Ohuchi, Michinori Funato, Shiori Ando, Satoshi Inagaki, Arisu Sato, Junko Seki, Chizuru Kawase, Kazuhiro Tsuruma, Ichizo Nishino, Shinsuke Nakamura, Masamitsu Shimazawa, Takashi Saito, Shin’ichi Takeda, Hideo Kaneko, Hideaki Hara
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Pharmacology
Subjects:
duchenne muscular dystrophy
prednisolone
utrophin
laminin
MMP-2
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01402/full

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https://www.frontiersin.org/article/10.3389/fphar.2018.01402/full

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