Ang II Promotes Cardiac Autophagy and Hypertrophy via Orai1/STIM1

Ang II Promotes Cardiac Autophagy and Hypertrophy via Orai1/STIM1

The pathophysiology of cardiac hypertrophy is complex and multifactorial. Both the store-operated Ca2+ entry (SOCE) and excessive autophagy are the major causative factors for pathological cardiac hypertrophy. However, it is unclear whether these two causative factors are interdependent. In this stu...

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Bibliographic Details
Main Authors: Chang-Bo Zheng, Wen-Cong Gao, Mingxu Xie, Zhichao Li, Xin Ma, Wencong Song, Dan Luo, Yongxiang Huang, Jichen Yang, Peng Zhang, Yu Huang, Weimin Yang, Xiaoqiang Yao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Pharmacology
Subjects:
angiotensin II
autophagy
Cardiac hypertrophy
orai1
STIM1
SOCE
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.622774/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.622774/full

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