Real-Time Molecular Monitoring in Acute Myeloid Leukemia With Circulating Tumor DNA

Real-Time Molecular Monitoring in Acute Myeloid Leukemia With Circulating Tumor DNA

The clonal evolution of acute myeloid leukemia (AML), an oligoclonal hematological malignancy, is driven by a plethora of cytogenetic abnormalities, gene mutations, abnormal epigenetic patterns, and aberrant gene expressions. These alterations in the leukemic blasts promote clinically diverse manife...

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Bibliographic Details
Main Authors: Deepshi Thakral, Ritu Gupta, Ranjit Kumar Sahoo, Pramod Verma, Indresh Kumar, Sangeeta Vashishtha
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
plasma cell free DNA
cfDNA
circulating tumor DNA
ctDNA
acute myeloid leukemia
genomic profiling
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.604391/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2020.604391/full

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