Effects of Fluoride on Submandibular Glands of Mice: Changes in Oxidative Biochemistry, Proteomic Profile, and Genotoxicity

Effects of Fluoride on Submandibular Glands of Mice: Changes in Oxidative Biochemistry, Proteomic Profile, and Genotoxicity

Although fluoride (F) is well-known to prevent dental caries, changes in cell processes in different tissues have been associated with its excessive exposure. Thus, this study aimed to evaluate the effects of F exposure on biochemical, proteomic, and genotoxic parameters of submandibular glands. Twe...

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Main Authors: Leidiane Alencar de Oliveira Lima, Giza Hellen Nonato Miranda, Walessa Alana Bragança Aragão, Leonardo Oliveira Bittencourt, Sávio Monteiro dos Santos, Michel Platini Caldas de Souza, Lygia S. Nogueira, Edivaldo Herculano Corrêa de Oliveira, Marta Chagas Monteiro, Aline Dionizio, Aline Lima Leite, Juliano Pelim Pessan, Marília Afonso Rabelo Buzalaf, Rafael Rodrigues Lima
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Pharmacology
Subjects:
submandibular gland
fluoride
toxicity
proteome
genotoxicity
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.715394/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.715394/full

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