Responses of DNA Mismatch Repair Proteins to a Stable G-Quadruplex Embedded into a DNA Duplex Structure

Responses of DNA Mismatch Repair Proteins to a Stable G-Quadruplex Embedded into a DNA Duplex Structure

DNA mismatch repair (MMR) plays a crucial role in the maintenance of genomic stability. The main MMR protein, MutS, was recently shown to recognize the G-quadruplex (G4) DNA structures, which, along with regulatory functions, have a negative impact on genome integrity. Here, we studied the effect of...

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Bibliographic Details
Main Authors: Anzhela V. Pavlova, Mayya V. Monakhova, Anna M. Ogloblina, Natalia A. Andreeva, Gennady Yu. Laptev, Vladimir I. Polshakov, Elizaveta S. Gromova, Maria I. Zvereva, Marianna G. Yakubovskaya, Tatiana S. Oretskaya, Elena A. Kubareva, Nina G. Dolinnaya
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
G-quadruplex
DNA mismatch repair
MutS
MutL
MutH
protein–DNA binding
Online Access:https://www.mdpi.com/1422-0067/21/22/8773

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https://www.mdpi.com/1422-0067/21/22/8773

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