Novel Features of dFMR1, the Drosophila Orthologue of the Fragile X Mental Retardation Protein

Novel Features of dFMR1, the Drosophila Orthologue of the Fragile X Mental Retardation Protein

FMRP belongs to a family of widely expressed proteins that contain RNA-binding domains. Although lack of human FMRP results in mental retardation, correlated with subtle synaptic changes, the precise role of FMRP remains elusive. The Drosophila genome contains a single gene homologous to the FXR fam...

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Bibliographic Details
Main Authors: Annette Schenck, Veronique Van de Bor, Barbara Bardoni, Angela Giangrande
Format: Article
Language:English
Published: Elsevier 2002-10-01
Series:Neurobiology of Disease
Subjects:
fragile X syndrome
mental retardation
FMRP
Drosophila melanogaster
dFMR1
posttranslational modification
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996102905103

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http://www.sciencedirect.com/science/article/pii/S0969996102905103

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