Replication and explorations of high-order epistasis using a large advanced intercross line pedigree.
Dissection of the genetic architecture of complex traits persists as a major challenge in biology; despite considerable efforts, much remains unclear including the role and importance of genetic interactions. This study provides empirical evidence for a strong and persistent contribution of both sec...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2011-07-01
|
| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC3140984?pdf=render |