A Collaborative Evaluation of LC-MS/MS Based Methods for BMAA Analysis: Soluble Bound BMAA Found to Be an Important Fraction

A Collaborative Evaluation of LC-MS/MS Based Methods for BMAA Analysis: Soluble Bound BMAA Found to Be an Important Fraction

Exposure to β-N-methylamino-l-alanine (BMAA) might be linked to the incidence of amyotrophic lateral sclerosis, Alzheimer’s disease and Parkinson’s disease. Analytical chemistry plays a crucial role in determining human BMAA exposure and the associated health risk, but the performance of various ana...

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Bibliographic Details
Main Authors: Elisabeth J. Faassen, Maria G. Antoniou, Wendy Beekman-Lukassen, Lucie Blahova, Ekaterina Chernova, Christophoros Christophoridis, Audrey Combes, Christine Edwards, Jutta Fastner, Joop Harmsen, Anastasia Hiskia, Leopold L. Ilag, Triantafyllos Kaloudis, Srdjan Lopicic, Miquel Lürling, Hanna Mazur-Marzec, Jussi Meriluoto, Cristina Porojan, Yehudit Viner-Mozzini, Nadezda Zguna
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:Marine Drugs
Subjects:
β-N-methylamino-
">l-alanine (BMAA)
6-aminoquinolyl-N-hydroxysuccinimidyl carbamate (AQC)
α,γ-diaminobutyric acid (DAB)
cycad
Daphnia magna
hydrophilic interaction liquid chromatography (HILIC)
Internal standard
Liquid chromatography-tandem mass spectrometry (LC-MS/MS)
N-(2-aminoethyl) glycine (AEG)
phytoplankton
seafood
Online Access:http://www.mdpi.com/1660-3397/14/3/45

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http://www.mdpi.com/1660-3397/14/3/45

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