Identification of low-confidence regions in the pig reference genome (Sscrofa10.2)

Identification of low-confidence regions in the pig reference genome (Sscrofa10.2)

Many applications of high throughput sequencing rely on the availability of an accurate reference genome. Variant calling often produces large data sets that cannot be realistically validated and which may contain large numbers of false-positives. Errors in the reference assembly increase the number...

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Bibliographic Details
Main Authors: Amanda eWarr, Christelle eRobert, David eHume, Alan L Archibald, Nader eDeeb, Mick eWatson
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Genetics
Subjects:
structural variation
False positives
Missassembly
Copy Number Variable Regions
Draft Assemblies
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00338/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00338/full

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