Annexin A5 regulates hepatic macrophage polarization via directly targeting PKM2 and ameliorates NASH

Annexin A5 regulates hepatic macrophage polarization via directly targeting PKM2 and ameliorates NASH

Nonalcoholic steatohepatitis (NASH), the progressive form of nonalcoholic fatty liver disease (NAFLD), is becoming a common chronic liver disease with the characteristics of steatosis, inflammation and fibrosis. Macrophage plays an important role in the development of NASH. In this study, Annexin A5...

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Bibliographic Details
Main Authors: Fang Xu, Mengmeng Guo, Wei Huang, Lili Feng, Jiazhen Zhu, Kangkang Luo, Jian Gao, Bingfeng Zheng, Ling-Dong Kong, Tao Pang, Xudong Wu, Qiang Xu
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Redox Biology
Subjects:
NASH
Macrophage polarization
Metabolic reprogramming
Annexin A5 (Anx A5)
PKM2
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720308399

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http://www.sciencedirect.com/science/article/pii/S2213231720308399

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