High expression of human carboxypeptidase M in Pichia pastoris: Purification and partial characterization

Carboxypeptidase M (CPM) is an extracellular glycosylphosphatidyl-inositol-anchored membrane glycoprotein, which removes the C-terminal basic residues, lysine and arginine, from peptides and proteins at neutral pH. CPM plays an important role in the control of peptide hormones and growth factor acti...

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Bibliographic Details
Main Authors: Craveiro R.B., Ramalho J.D., Chagas J.R., Wang P.H.M., Casarini D.E., Pesquero J.L., Araújo R.C., Pesquero J.B.
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2006-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000200007