Interferon-α abrogates tolerance induction by human tolerogenic dendritic cells.

BACKGROUND: Administration of interferon-α (IFN-α) represents an approved adjuvant therapy as reported for malignancies like melanoma and several viral infections. In malignant diseases, tolerance processes are critically involved in tumor progression. In this study, the effect of IFN-α on tolerance...

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Bibliographic Details
Main Authors: Nicole Bacher, Edith Graulich, Helmut Jonuleit, Stephan Grabbe, Kerstin Steinbrink
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3144929?pdf=render