Natural bizbenzoquinoline derivatives protect zebrafish lateral line sensory hair cells from aminoglycoside toxicity

Natural bizbenzoquinoline derivatives protect zebrafish lateral line sensory hair cells from aminoglycoside toxicity

Moderate to severe hearing loss affects 360 million people worldwide and most often results from damage to sensory hair cells. Hair cell damage can result from aging, genetic mutations, excess noise exposure, and certain medications including aminoglycoside antibiotics. Aminoglycosides are effective...

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Bibliographic Details
Main Authors: Matthew eKruger, Robert eBoney, Alexander eOrdoobadi, Thomas F Sommers, Josef G Trapani, Allison B Coffin
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Aminoglycosides
Cisplatin
Hearing Loss
Zebrafish
Lateral Line
ototoxicity
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00083/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00083/full

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