Real-time assembly of ribonucleoprotein complexes on nascent RNA transcripts

The early steps of ribosome assembly occur co-transcriptionally on the nascent ribosomal RNA. Here the authors demonstrate an approach that allows simultaneous monitoring of transcription and ribosomal protein assembly at the single-molecule level in real time.

Bibliographic Details
Main Authors: Olivier Duss, Galina A. Stepanyuk, Annette Grot, Seán E. O’Leary, Joseph D. Puglisi, James R. Williamson
Format: Article
Language:English
Published: Nature Publishing Group 2018-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-07423-3