Site-specific glycosaminoglycan content is better maintained in the pericellular matrix than the extracellular matrix in early post-traumatic osteoarthritis.

Site-specific glycosaminoglycan content is better maintained in the pericellular matrix than the extracellular matrix in early post-traumatic osteoarthritis.

One of the characteristics of early osteoarthritis (OA) is the loss of fixed charged density (FCD) of glycosaminoglycans in the superficial zone of articular cartilage. However, possible local changes in the FCD content of the pericellular matrix (PCM) are not fully understood. Hence, our aim was to...

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Bibliographic Details
Main Authors: Simo P Ojanen, Mikko A J Finnilä, Aino E Reunamo, Ari P Ronkainen, Santtu Mikkonen, Walter Herzog, Simo Saarakkala, Rami K Korhonen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5919041?pdf=render

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http://europepmc.org/articles/PMC5919041?pdf=render

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