Non-invasive Detection of Exosomal MicroRNAs via Tethered Cationic Lipoplex Nanoparticles (tCLN) Biochip for Lung Cancer Early Detection

Non-invasive Detection of Exosomal MicroRNAs via Tethered Cationic Lipoplex Nanoparticles (tCLN) Biochip for Lung Cancer Early Detection

Circulating microRNAs carried by exosomes have emerged as promising diagnostic biomarkers for cancer because of their abundant amount and remarkable stability in body fluids. Exosomal microRNAs in blood are typically quantified using the RNA isolation-qRT-PCR workflow, which cannot distinguish circu...

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Bibliographic Details
Main Authors: Chang Liu, Eric Kannisto, Guan Yu, Yunchen Yang, Mary E. Reid, Santosh K. Patnaik, Yun Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Genetics
Subjects:
exosomes
circulating microRNAs
cancer biomarker
liquid biopsy
lung cancer
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00258/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2020.00258/full

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