The Notch-mediated hyperplasia circuitry in Drosophila reveals a Src-JNK signaling axis

Notch signaling controls a wide range of cell fate decisions during development and disease via synergistic interactions with other signaling pathways. Here, through a genome-wide genetic screen in Drosophila, we uncover a highly complex Notch-dependent genetic circuitry that profoundly affects prol...

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Bibliographic Details
Main Authors: Diana M Ho, SK Pallavi, Spyros Artavanis-Tsakonas
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-07-01
Series:eLife
Subjects:
Src
JNK
Online Access:https://elifesciences.org/articles/05996