Molecular targets and signaling pathways regulated by nuclear translocation of syndecan-1

Molecular targets and signaling pathways regulated by nuclear translocation of syndecan-1

Abstract Background The cell-surface heparan sulfate proteoglycan syndecan-1 is important for tumor cell proliferation, migration, and cell cycle regulation in a broad spectrum of malignancies. Syndecan-1, however, also translocates to the cell nucleus, where it might regulate various molecular func...

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Bibliographic Details
Main Authors: Tünde Szatmári, Filip Mundt, Ashish Kumar-Singh, Lena Möbus, Rita Ötvös, Anders Hjerpe, Katalin Dobra
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Cell Biology
Subjects:
Syndecan-1
Nuclear localization
Transcriptomic
Proteomic
Pathway analysis
Proliferation
Online Access:http://link.springer.com/article/10.1186/s12860-017-0150-z

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http://link.springer.com/article/10.1186/s12860-017-0150-z

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