Oral lipid-based nanoformulation of tafenoquine enhanced bioavailability and blood stage antimalarial efficacy and led to a reduction in human red blood cell loss in mice

Paula Melariri,1 Lonji Kalombo,2 Patric Nkuna,2 Admire Dube,2,3 Rose Hayeshi,2 Benhards Ogutu,4,5 Liezl Gibhard,6 Carmen deKock,6 Peter Smith,6 Lubbe Wiesner,6 Hulda Swai2 1Polymers and Composites, Material Science and Manufacturing, Council for Scientific and Industrial Research, Port Elizabeth,...

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Bibliographic Details
Main Authors: Melariri P, Kalombo L, Nkuna P, Dube A, Hayeshi R, Ogutu B, Gibhard L, deKock C, Smith P, Wiesner L, Swai H
Format: Article
Language:English
Published: Dove Medical Press 2015-02-01
Series:International Journal of Nanomedicine
Online Access:http://www.dovepress.com/oral-lipid-based-nanoformulation-of-tafenoquine-enhanced-bioavailabili-peer-reviewed-article-IJN