Functional interaction between Wnt and Bmp signaling in periosteal bone growth

Abstract Wnt and Bmp proteins are well known to regulate bone development and homeostasis. Although both signals are extensively studied, their potential interaction in vivo is less well understood. Previous studies have shown that deletion of Bmpr1a, a type I receptor for Bmp signaling, results in...

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Bibliographic Details
Main Authors: Deye Song, Guangxu He, Yu Shi, Jiangdong Ni, Fanxin Long
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-90324-1