Peptide synthesis: ball-milling, in solution, or on solid support, what is the best strategy?

While presenting particularly interesting advantages, peptide synthesis by ball-milling was never compared to the two traditional strategies, namely peptide syntheses in solution and on solid support (solid-phase peptide synthesis, SPPS). In this study, the challenging VVIA tetrapeptide was synthesi...

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Bibliographic Details
Main Authors: Ophélie Maurin, Pascal Verdié, Gilles Subra, Frédéric Lamaty, Jean Martinez, Thomas-Xavier Métro
Format: Article
Language:English
Published: Beilstein-Institut 2017-10-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.13.206