Structure of the protective nematode protease complex H-gal-GP and its conservation across roundworm parasites.

Roundworm parasite infections are a major cause of human and livestock disease worldwide and a threat to global food security. Disease control currently relies on anthelmintic drugs to which roundworms are becoming increasingly resistant. An alternative approach is control by vaccination and 'h...

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Bibliographic Details
Main Authors: Charlotte A Scarff, Rebecca F Thompson, George F J Newlands, Alexander H Jamson, Christopher Kennaway, Vivian J da Silva, Elida M Rabelo, Chun-Feng Song, John Trinick, W David Smith, Stephen P Muench
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-04-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008465