A Cecal Slurry Mouse Model of Sepsis Leads to Acute Consumption of Vitamin C in the Brain

A Cecal Slurry Mouse Model of Sepsis Leads to Acute Consumption of Vitamin C in the Brain

Vitamin C (ascorbate, ASC) is a critical antioxidant in the body with specific roles in the brain. Despite a recent interest in vitamin C therapies for critical care medicine, little is known about vitamin C regulation during acute inflammation and critical illnesses such as sepsis. Using a cecal sl...

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Bibliographic Details
Main Authors: David C. Consoli, Jordan J. Jesse, Kelly R. Klimo, Adriana A. Tienda, Nathan D. Putz, Julie A. Bastarache, Fiona E. Harrison
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Nutrients
Subjects:
vitamin c
ascorbate
sepsis
brain
cecal slurry
inflammation
cytokines
mouse
Online Access:https://www.mdpi.com/2072-6643/12/4/911

Internet

https://www.mdpi.com/2072-6643/12/4/911

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