Imipramine protects retinal ganglion cells from oxidative stress through the tyrosine kinase receptor B signaling pathway

Imipramine protects retinal ganglion cells from oxidative stress through the tyrosine kinase receptor B signaling pathway

Retinal ganglion cell (RGC) degeneration is irreversible in glaucoma and tyrosine kinase receptor B (TrkB)-associated signaling pathways have been implicated in the process. In this study, we attempted to examine whether imipramine, a tricyclic antidepressant, may protect hydrogen peroxide (H 2 O 2...

Full description

Bibliographic Details
Main Authors: Ming-lei Han, Guo-hua Liu, Jin Guo, Shu-juan Yu, Jing Huang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; retinal ganglion cell; imipramine; oxidative stress; apoptosis; tyrosine kinase receptor B; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2016;volume=11;issue=3;spage=476;epage=479;aulast=

Internet

http://www.nrronline.org/article.asp?issn=1673-5374;year=2016;volume=11;issue=3;spage=476;epage=479;aulast=

Similar Items