Addressing uncertainty in genome-scale metabolic model reconstruction and analysis
Abstract The reconstruction and analysis of genome-scale metabolic models constitutes a powerful systems biology approach, with applications ranging from basic understanding of genotype-phenotype mapping to solving biomedical and environmental problems. However, the biological insight obtained from...
Main Authors: | David B. Bernstein, Snorre Sulheim, Eivind Almaas, Daniel Segrè |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-02-01
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Series: | Genome Biology |
Online Access: | https://doi.org/10.1186/s13059-021-02289-z |
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