3C and 3C-based techniques: the powerful tools for spatial genome organization deciphering

Abstract It is well known that the chromosomes are organized in the nucleus and this spatial arrangement of genome play a crucial role in gene regulation and genome stability. Different techniques have been developed and applied to uncover the intrinsic mechanism of genome architecture, especially t...

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Bibliographic Details
Main Authors: Jinlei Han, Zhiliang Zhang, Kai Wang
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Molecular Cytogenetics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13039-018-0368-2