3C and 3C-based techniques: the powerful tools for spatial genome organization deciphering
Abstract It is well known that the chromosomes are organized in the nucleus and this spatial arrangement of genome play a crucial role in gene regulation and genome stability. Different techniques have been developed and applied to uncover the intrinsic mechanism of genome architecture, especially t...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-03-01
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Series: | Molecular Cytogenetics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13039-018-0368-2 |