Autism and increased paternal age related changes in global levels of gene expression regulation.

A causal role of mutations in multiple general transcription factors in neurodevelopmental disorders including autism suggested that alterations in global levels of gene expression regulation might also relate to disease risk in sporadic cases of autism. This premise can be tested by evaluating for...

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Bibliographic Details
Main Authors: Mark D Alter, Rutwik Kharkar, Keri E Ramsey, David W Craig, Raun D Melmed, Theresa A Grebe, R Curtis Bay, Sharman Ober-Reynolds, Janet Kirwan, Josh J Jones, J Blake Turner, Rene Hen, Dietrich A Stephan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3040743?pdf=render