Post-transplantation Cyclophosphamide: From HLA-Haploidentical to Matched-Related and Matched-Unrelated Donor Blood and Marrow Transplantation

Post-transplantation Cyclophosphamide: From HLA-Haploidentical to Matched-Related and Matched-Unrelated Donor Blood and Marrow Transplantation

Following allogeneic blood and marrow transplantation (BMT), graft-versus-host disease (GvHD) continues to represent a significant cause of treatment failure, despite the routine use of conventional, mainly calcineurin inhibitor-based prophylaxis. Recently, post-transplant cyclophosphamide (PTCy) ha...

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Bibliographic Details
Main Authors: Louis Williams, Frank Cirrone, Kelli Cole, Maher Abdul-Hay, Leo Luznik, Ahmad Samer Al-Homsi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Immunology
Subjects:
GvHD prevention
post-transplant cyclophosphamide
matched-related donor
matched unrelated donor
bortezomib
calcineurin inhibitor-free
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00636/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00636/full

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