Rif1 regulates initiation timing of late replication origins throughout the S. cerevisiae genome.

Chromosomal DNA replication involves the coordinated activity of hundreds to thousands of replication origins. Individual replication origins are subject to epigenetic regulation of their activity during S-phase, resulting in differential efficiencies and timings of replication initiation during S-p...

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Bibliographic Details
Main Authors: Jared M Peace, Anna Ter-Zakarian, Oscar M Aparicio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4039536?pdf=render