ApoA-IV promotes the biogenesis of apoA-IV-containing HDL particles with the participation of ABCA1 and LCAT[S]

ApoA-IV promotes the biogenesis of apoA-IV-containing HDL particles with the participation of ABCA1 and LCAT[S]

The objective of this study was to establish the role of apoA-IV, ABCA1, and LCAT in the biogenesis of apoA-IV-containing HDL (HDL-A-IV) using different mouse models. Adenovirus-mediated gene transfer of apoA-IV in apoA-I−/− mice did not change plasma lipid levels. ApoA-IV floated in the HDL2/HDL3 r...

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Bibliographic Details
Main Authors: Adelina Duka, Panagiotis Fotakis, Dimitra Georgiadou, Andreas Kateifides, Kalliopi Tzavlaki, Leonard von Eckardstein, Efstratios Stratikos, Dimitris Kardassis, Vassilis I. Zannis
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Journal of Lipid Research
Subjects:
apolipoprotein A-IV
lipoproteins
genetically altered mice
lecithin:cholesterol acyltransferase
ATP binding cassette transporter A1
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520417663

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http://www.sciencedirect.com/science/article/pii/S0022227520417663

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