p62‐mediated autophagy affects nutrition‐dependent insulin receptor substrate 1 dynamics in 3T3‐L1 preadipocytes

Abstract Aims/Introduction Previous studies have shown that an organism's nutritional status changes the protein levels of insulin receptor substrate 1 (IRS‐1) in a tissue‐specific manner. Although the mechanisms underlying the regulation of IRS‐1 in the nutrient‐rich conditions associated with...

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Bibliographic Details
Main Authors: Hirobumi Igawa, Akihiro Kikuchi, Hirofumi Misu, Kiyo‐aki Ishii, Shuichi Kaneko, Toshinari Takamura
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Journal of Diabetes Investigation
Subjects:
p62
Online Access:https://doi.org/10.1111/jdi.12866