Efficacy of MEK inhibition in a recurrent malignant peripheral nerve sheath tumor

Efficacy of MEK inhibition in a recurrent malignant peripheral nerve sheath tumor

Abstract The prognosis of recurrent malignant peripheral nerve sheath tumors (MPNST) is dismal, with surgical resection being the only definitive salvage therapy. Treatment with chemoradiation approaches has not significantly improved patient outcomes. Similarly, trials of therapies targeting MPNST...

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Bibliographic Details
Main Authors: Sumanth Nagabushan, Loretta M. S. Lau, Paulette Barahona, Marie Wong, Alexandra Sherstyuk, Glenn M. Marshall, Vanessa Tyrrell, Eva A. Wegner, Paul G. Ekert, Mark J. Cowley, Chelsea Mayoh, Toby N. Trahair, Philip Crowe, Antoinette Anazodo, David S. Ziegler
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-021-00145-8

Internet

https://doi.org/10.1038/s41698-021-00145-8

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