Association of HLA class II alleles and CTLA-4 polymorphism with type 1 diabetes

Type-1 diabetes mellitus (T1DM) is a progressive complex autoimmune disease in which combinations of environmental as well as genetic factors contribute to T-cell mediated destruction of insulin-secreting β-cells of the pancreas. HLA class II alleles on chromosome 6p21 [insulin dependent diabetes me...

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Bibliographic Details
Main Authors: Rana J EI Wafai, Hania Nakkash Chmaisse, Rajaa F Makki, Hana Fakhoury
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2011-01-01
Series:Saudi Journal of Kidney Diseases and Transplantation
Online Access:http://www.sjkdt.org/article.asp?issn=1319-2442;year=2011;volume=22;issue=2;spage=273;epage=281;aulast=EI