Granulocyte colony-stimulating factor and leukemogenesis

THE granulocyte colony-stimulating factor (G-CSF) plays an important role in normal granulopoiesis. Its functions are mediated by specific receptors on the surface of responsive cells and, upon ligand binding, several cytoplasmic tyrosine kinases are activated. The cytoplasmic region proximal to the...

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Bibliographic Details
Main Authors: Lorena Lobo de Figueiredo, Rodrigo Siqueira de Abreu e Lima, Eduardo Magalhães Rego
Format: Article
Language:English
Published: Hindawi Limited 2004-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1080/09511920410001713574