Granulocyte colony-stimulating factor and leukemogenesis
THE granulocyte colony-stimulating factor (G-CSF) plays an important role in normal granulopoiesis. Its functions are mediated by specific receptors on the surface of responsive cells and, upon ligand binding, several cytoplasmic tyrosine kinases are activated. The cytoplasmic region proximal to the...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2004-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1080/09511920410001713574 |