Longitudinal ex vivo and molecular trends of chloroquine and piperaquine activity against Plasmodium falciparum and P. vivax before and after introduction of artemisinin-based combination therapy in Papua, Indonesia

Longitudinal ex vivo and molecular trends of chloroquine and piperaquine activity against Plasmodium falciparum and P. vivax before and after introduction of artemisinin-based combination therapy in Papua, Indonesia

Drug resistant Plasmodium parasites are a major threat to malaria control and elimination. After reports of high levels of multidrug resistant P. falciparum and P. vivax in Indonesia, in 2005, the national first-line treatment policy for uncomplicated malaria was changed in March 2006, to dihydroart...

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Bibliographic Details
Main Authors: Jutta Marfurt, Grennady Wirjanata, Pak Prayoga, Ferryanto Chalfein, Leo Leonardo, Boni F. Sebayang, Dwi Apriyanti, Maic A.E.M. Sihombing, Leily Trianty, Rossarin Suwanarusk, Alan Brockman, Kim A. Piera, Irene Luo, Angela Rumaseb, Barbara MacHunter, Sarah Auburn, Nicholas M. Anstey, Enny Kenangalem, Rintis Noviyanti, Bruce Russell, Jeanne R. Poespoprodjo, Ric N. Price
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Subjects:
Malaria
Plasmodium falciparum
Plasmodium vivax
Chloroquine
Piperaquine
Drug resistance
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320721000294

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http://www.sciencedirect.com/science/article/pii/S2211320721000294

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