A randomized phase 2B trial of vancomycin versus daptomycin for the treatment of methicillin-resistant Staphylococcus aureus bacteremia due to isolates with high vancomycin minimum inhibitory concentrations – results of a prematurely terminated study

A randomized phase 2B trial of vancomycin versus daptomycin for the treatment of methicillin-resistant Staphylococcus aureus bacteremia due to isolates with high vancomycin minimum inhibitory concentrations – results of a prematurely terminated study

Abstract Background Studies have suggested the reduced effectiveness of vancomycin against methicillin-resistant Staphylococcus aureus (MRSA) bloodstream infections with high vancomycin minimum inhibitory concentrations. Alternative agents such as daptomycin may be considered. We conducted a randomi...

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Bibliographic Details
Main Authors: Shirin Kalimuddin, Yvonne F. Z. Chan, Rachel Phillips, Siew Pei Ong, Sophia Archuleta, David Chien Lye, Thuan Tong Tan, Jenny G. H. Low
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Trials
Subjects:
Methicillin-resistant Staphylococcus aureus
Vancomycin
Daptomycin
Minimum inhibitory concentration
Bacteremia
Online Access:http://link.springer.com/article/10.1186/s13063-018-2702-8

Internet

http://link.springer.com/article/10.1186/s13063-018-2702-8

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