Ketogenic diet restrains aging-induced exacerbation of coronavirus infection in mice

Ketogenic diet restrains aging-induced exacerbation of coronavirus infection in mice

Increasing age is the strongest predictor of risk of COVID-19 severity and mortality. Immunometabolic switch from glycolysis to ketolysis protects against inflammatory damage and influenza infection in adults. To investigate how age compromises defense against coronavirus infection, and whether a pr...

Full description

Bibliographic Details
Main Authors: Seungjin Ryu, Irina Shchukina, Yun-Hee Youm, Hua Qing, Brandon Hilliard, Tamara Dlugos, Xinbo Zhang, Yuki Yasumoto, Carmen J Booth, Carlos Fernández-Hernando, Yajaira Suárez, Kamal Khanna, Tamas L Horvath, Marcelo O Dietrich, Maxim Artyomov, Andrew Wang, Vishwa Deep Dixit
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-06-01
Series:eLife
Subjects:
aging
MHV
coronavirus
inflammasome
gamma delta t cell
ketogenic diet
Online Access:https://elifesciences.org/articles/66522

Internet

https://elifesciences.org/articles/66522

Similar Items