Multi-Layer Identification of Highly-Potent ABCA1 Up-Regulators Targeting LXRβ Using Multiple QSAR Modeling, Structural Similarity Analysis, and Molecular Docking

Multi-Layer Identification of Highly-Potent ABCA1 Up-Regulators Targeting LXRβ Using Multiple QSAR Modeling, Structural Similarity Analysis, and Molecular Docking

In this study, in silico approaches, including multiple QSAR modeling, structural similarity analysis, and molecular docking, were applied to develop QSAR classification models as a fast screening tool for identifying highly-potent ABCA1 up-regulators targeting LXRβ based on a series of new flavonoi...

Full description

Bibliographic Details
Main Authors: Meimei Chen, Fafu Yang, Jie Kang, Xuemei Yang, Xinmei Lai, Yuxing Gao
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Molecules
Subjects:
ABCA1
QSAR
molecular modeling
similarity analysis
molecular docking
LXRβ
Online Access:http://www.mdpi.com/1420-3049/21/12/1639

Internet

http://www.mdpi.com/1420-3049/21/12/1639

Similar Items